We thrive to explore the boundaries of neuroscience knowledge
The scientific focus of our lab is to understand the mechanisms involved in the earliest stages of neurodegenerative disease in order to deliver therapeutic targets with the greatest potential to prevent dementia and Parkinson’s disease. We are based in the newly established UK Dementia Research Institute (UK DRI) at the University of Cambridge. UK DRI is a collaborative, inter-disciplinary Centre, combining world-leading expertise unique to Cambridge from chemistry, biophysics and structural biology with internationally leading research in the biology of neurodegeneration. The Metzakopian lab employs a variety of state of the art techniques and disease models towards implementing innovative experimental approaches that will help us test our hypotheses. These include, but are not limited to, CRISPR-Cas9 genetic screens and single-cell transcriptomics in human induced pluripotent stem cell derived neurons. By providing a stimulating, interactive, and cooperative research environment that supports independent thinking, our group provides an excellent platform for personal and professional development.